The Benefits of Exercise

It has been established with men with PCA, even when undertaking androgen deprivation (hormone therapy) that a combination of high-load resistance exercise and 20 min of aerobic exercise, 3 times a week, can:

  1. Both preserve and increase strength, muscle mass and reduce fat, even if the men are simultaneously undergoing radiotherapy [1].
  2. Reduce physiological distress and improve social functioning [2].
  3. Improve sexual function [2,3].
  4. Reduce fatigue [2,4].
  5. Help preserve bone strength and density (necessary against osteoporosis) [5].
  6. Be safely performed during radiotherapy, androgen deprivation, even in the presence of bone metastases [6].
  7. Can help preserve improve muscle and physical performance when performed prior to prostatectomy [7].


To see a list of our ongoing clinical trials where you can participate for free, please visit or email us at



Newton RU, Mavropalias G, Fragala MS, Kraemer WJ, Häkkinen K, Taaffe DR, et al. Radiotherapy before or during androgen-deprivation therapy does not blunt the exercise-induced body composition protective effects in prostate cancer patients: A secondary analysis of two randomized controlled trials. Exp Gerontol 2021;151:111427.


Cormie P, Galvão DA, Spry N, Joseph D, Chee R, Taaffe DR, et al. Can supervised exercise prevent treatment toxicity in patients with prostate cancer initiating androgen-deprivation therapy: a randomised controlled trial. BJU Int 2015;115:256–66.


Cormie P, Newton RU, Taaffe DR, Spry N, Joseph D, Akhlil Hamid M, et al. Exercise maintains sexual activity in men undergoing androgen suppression for prostate cancer: a randomized controlled trial. Prostate Cancer Prostatic Dis 2013;16:170–5.


Taaffe DR, Newton RU, Spry N, Joseph D, Chambers SK, Gardiner RA, et al. Effects of different exercise modalities on fatigue in prostate cancer patients undergoing androgen deprivation therapy: a year-long randomised controlled trial. Eur Urol 2017;72:293–9.


Taaffe DR, Galvão DA, Spry N, Joseph D, Chambers SK, Gardiner RA, et al. Immediate versus delayed exercise in men initiating androgen deprivation: effects on bone density and soft tissue composition. BJU Int 2019;123:261–9.


Galvão DA, Taaffe DR, Spry N, Cormie P, Joseph D, Chambers SK, et al. Exercise preserves physical function in prostate cancer patients with bone metastases. Med Sci Sports Exerc 2018;50:393–9.


Singh F, Newton RU, Baker MK, Spry NA, Taaffe DR, Thavaseelan J, et al. Feasibility of presurgical exercise in men with prostate cancer undergoing prostatectomy. Integr Cancer Ther 2017;16:290–9.